The Department of Chemistry

Faculty

Matthew D. Disney

Matthew DisneyAssistant Professor
Office: 657 Natural Sciences Complex
Phone: (716) 645-4242
Fax: (716) 645-6963
E-mail: mddisney@buffalo.edu
Lab website: http://prof.dr.disney.googlepages.com/
Information on the Disney Research Group

 

Publication List:

  1. Testa SM, Disney MD, Turner DH, and Kierzek R.  Thermodynamics of RNA-RNA Duplexes with 2- or 4-Thiouridines:  Implications for Antisense Design and Targeting a Group I Intron.  Biochemistry, (1999), 38, 16655-16662.
  2. Disney MD, Testa SM, and Turner DH.  Targeting a Pneumocystis carinii Group I Intron with Methylphosphonate Oligonucleotides:  Backbone Charge is Not Required for Binding or Reactivity.  Biochemistry, (2000), 39, 6991-7000.
  3. Disney MD, Gryaznov SM, and Turner DH. Contributions of Individual Nucleotides to Tertiary Binding of Substrate by a Pneumocystis carinii Group I Intron.  Biochemistry, (2000), 39, 14269-14278.
  4. Disney MD, Haidaris CG, and Turner DH.  Recognition Elements for 5' Exon Substrate Binding to the Candida albicans Group I Intron.  Biochemistry, (2001), 40, 6507-6519.
  5. Disney MD, Matray T, Gryaznov SM, and Turner DH.  Binding Enhancement by Tertiary Interactions and Suicide Inhibition of a Candida albicans Group I Intron by Phosphoramidate and 2' O-Methyl Hexanucleotides.  Biochemistry, (2001), 40, 6520-6526.
  6. Disney MD and Turner DH.  Tertiary Interactions with an Imino G·A Pair Facilitate Binding of the 5' Exon and Guanosine Substrates to the Candida albicans Group I Intron.  Biochemistry, (2002), 41, 8113-8119.
  7. Childs JL, Disney MD, and Turner DH.  Oligonucleotide Directed Misfolding of RNA (ODMir) Inhibits Group I Intron Self-Splicing.  Proceedings of the National Academy of Sciences USA, (2002), 99, 11091-11096.
  8. Disney MD, Haidaris, CG, and Turner DH.  Uptake and Antifungal Activity of Oligonucleotides in Candida albicans.  Proceedings of the National Academy of Sciences USA, (2003), 100, 1530-1534.
  9. Du H, Disney MD, Miller BL, and Krauss T.  Hybridization-Based Unquenching of DNA Hairpins on Au Surfaces:  Prototypical "Molecular Beacon" Biosensors.  Journal of the American Chemical Society, (2003), 125, 4012-4013.
  10. Mathews DH, Disney MD, Childs JL, Schroeder SJ, Zucker M, and Turner DH.  Incorporating Chemical Modification Restraints into a Dynamic Programming Algorithm Improves Prediction of RNA Secondary Structure.  Proceedings of the National Academy of Sciences USA, (2004), 101, 7287-7292.
  11. Disney MD, Childs JL, and Turner DH.  Targeting RNA with Oligonucleotides:  Inhibition of Group I Intron Self-Splicing. Biopolymers, (2004), 73, 151-161.
  12. Disney MD, Magnet S, Blanchard JS, and Seeberger PH.  Aminoglycoside Microarrays to Study Antibiotic Resistance.  Angewandte Chemie International Edition, (2004), 43, 1591-1594.
  13. Disney MD and Seeberger PH.  Aminoglycoside Microarrays to Explore Carbohydrate-RNA Interactions.  Chemistry-A European Journal, (2004), 10, 3308-3314.
  14. Disney MD and Seeberger PH.  Carbohydrate Arrays as Tools in Glycomics.  Drug Discovery Today: Tools, (2004), 4, 151-158.
  15. Disney MD, Zheng J, Swager T, and Seeberger PH.  Detection of Escherichia coli with Carbohydrate-Functionalized Fluorescent Polymers. Journal of the American Chemical Society, (2004), 126, 13343-13346.
  16. Ratner DM, Adams EA, Disney MD, and Seeberger PH.  Carbohydrate Microarrays as Tools to Probe Glycobiology. ChemBioChem, (2004), 5, 1375-1383.
  17. Disney MD, Childs JL, and Turner DH. Hoechst 33258 Inhibits Group I Intron Self-Splicing by Affecting RNA Folding. ChemBioChem, (2004), 5, 1647-1652.
  18. Disney MD and Seeberger PH.  Carbohydrate Arrays to Probe Cell Adhesion and to Facilitate Pathogen Detection.  Chemistry and Biology, (2004), 11, 1701-1707.
  19. Disney MD, Stephenson R, Wright TW, Haidaris CG, Turner DH, and Gigliotti F. Antimicrobial Activity of Hoechst 33258 against Pneumocystis carinii, F. sp. muris, Candida albicans, and Candida dubliniensis.  Antimicrobial Agents Chemotherapy, (2005), 49, 1326-1330.
  20. Brun MA, Disney MD, Seeberger PH.  Miniaturization of Microwave-Assisted Carbohydrate Fictionalization to Create Oligosaccharide Microarrays. ChemBioChem, (2006), 7, 421-424.
  21. Kehr J-C, Zilliges Y, Disney MD, Ratner DM, Bouchier C, Seeberger PH, Tandeau de Marsac N, Dittmann E.  A Mannan Binding Lectin is Involved in Cell–Cell Attachment in a Toxic Strain of Microcystis aeruginosa.  Mol Microbiol., (2006), 59, 893-906.
  22. Disney MD, Hook D, Namamoto K, Seeberger PH, Seebach D. N-Linked Glycosylated ß-Peptides are Resistant to Degradation by Glycoamidase A.  Chemistry & Biodiversity, (2005), 2, 1624-1634.
  23. Barrett OJ, Childs JL, Disney MD.  Chemical Microarrays to Identify Ligands that Bind Pathogenic Cells.  ChemBioChem, (2006), 7, 1882-1885.
  24. Disney, MD and Childs-Disney, JL.  Using Selection to Identify a Chemical Microarray to Study the RNA Internal Loops Recognized by 6' Acetylated Kanamycin A. ChemBioChem, (2007), 8, 649-656.
  25. Childs-Disney JL, Wu M, Pushechnikov A, Aminova O, and Disney MD.  A Small Molecule Microarray-Based Method to Select RNA Internal Loop-Ligand Interactions.  ACS-Chemical Biology, (2007), 2, 745-754.
  26. Disney MD and Barrett OJ.  An Aminoglycoside Microarray Platform to Directly Monitor and Study Resistance.  Biochemistry, (2007), 46, 11223-11230.
  27. Disney MD and Childs-Disney JL.  "Supra"molecular Recognition of Galectin-1.  Chemistry & Biology, (2007), 14, 1095-1097.
  28. Disney MD.  Book Review:  Biochips as Pathways to Drug Discovery. Edited by Andrew Carmen and Gary Hardiman.  ChemMedChem, (2008), 3, No. 02, 363.
  29. Childs-Disney, JL and Disney, MD.  A Simple Method to Increase the Information Density in Sequencing Experiments Used to Deconvolute Nucleic Acid Selections.  RNA, (2008), 14, 390-394.
  30. Disney MD, Labuda LP, Paul DJ, Poplawski SG, Pushechnikov A, Tran T, Velagapudi SP, Wu M, and Childs-Disney JL.  Two-Dimensional Combinatorial Screening Identifies Specific Aminoglycoside-RNA Internal Loop Partners. Journal of the American Chemical Society, (2008), 130, 11185-11194.
  31. Barrett OJ, Pushechnikov A, Wu M, and Disney MD.  Studying Aminoglycoside Modification by the Acetyltransferase Class of Resistance-Causing Enzymes via Microarray.  Carbohydrate Research, (2008), 343, 2924-2931.
  32. Aminova O, Paul DJ, Childs-Disney JL, and Disney MD. Two-Dimensional Combinatorial Screening Identifies Specific 6' Acylated Kanamycin A and 6' Acylated Neamine-RNA Hairpin Interactions. Biochemistry, (2008), 47, 12670-12679.
  33. Aminova O and Disney MD.  A Microarray-Based Method to Complete Nucleic Acid Selections. Methods in Molecular Biology, in press.
  34. Labuda LP, Pushechnikov A, and Disney MD.  Small Molecule Microarrays of RNA-Focused Peptoids Help Identify Inhibitors of a Pathogenic Group I Intron. ACS-Chemical Biology, in press.  Cover Article.
  35. Disney MD. Short Circuiting RNA Splicing, Nature Chemical Biology, (2008), 4, 723-724.
  36. Lee MM, Pushechnikov A, and Disney MD.  Rationally Designed Ligands that Target the RNA that Causes Myotonic Muscular Dystrophy Type 2. ACS-Chemical Biology, in press.

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The Department of Chemistry