The Department of Chemistry

Faculty

Qing Lin

Qing LinAssistant Professor
Office: 679 Natural Sciences Complex
Phone: (716) 645-4254
Fax: (716) 645-6963
E-mail: qinglin@buffalo.edu
Information on the Lin Research Group

 

 

Publication List:

  1. Michael M. Madden, Claudia I. Rivera Vera, Wenjiao Song, and Qing Lin* "Facile Synthesis of Stapled, Structurally Reinforced Peptide Helices via A Photoinduced Intramolecular 1,3-Dipolar Cycloaddition Reaction" Chem. Commun. 2009, 5588-5590.
  2. Yizhong Wang and Qing Lin* "Synthesis and Evaluation of Photoreactive Tetrazole Amino Acids" Org. Lett. 2009, 3570-3573.
  3. Yizhong Wang, Wenjiao Song, Wen J. Hu, and Qing Lin* "Fast Alkene Functionalization In Vivo by Photoclick Chemistry: HOMO-Lifting of Nitrile Imine Dipoles" Angew. Chem. Int. Ed. 2009, 48, 5330-5333.
  4. Qing Lin*, and Reyna K. V. Lim "Traceless Native Protein Labeling In Mice" Nature Chem. Biol. 2009, 5, 275-276 (News & Views Article).
  5. Yizhong Wang, Wen J. Hu, Wenjiao Song, Reyna K. V. Lim, and Qing Lin* "Discovery of Long-Wavelength Photoactivatable Diaryltetrazoles for Bioorthogonal 1,3-Dipolar Cycloaddition Reactions" Org. Lett. 2008, 10,  3725-3728.
  6. Wenjiao Song, Yizhong Wang, Jun Qu, and Qing Lin* "Selective Functionalization of a Genetically Encoded Alkene-Containing Protein via “Photoclick Chemistry” in Bacterial Cells" J. Am. Chem. Soc. 2008, 130, 9654-9655.
  7. Wenjiao Song, Yizhong Wang, Jun Qu, Michael M. Madden, and Qing Lin* "A Photoinducible 1,3-Dipolar Cycloaddition Reaction for Rapid, Selective Modification of Tetrazole-Containing Proteins" Angew. Chem. Int. Ed. 2008, 47, 2832-2835.
  8. Michael M. Madden, Wenjiao Song, Paul G. Martell, Yong Ren, Jian Feng, and Qing Lin* "Substrate Properties of Ubiquitin Carboxyl-Terminally Derived Peptide Probes for Protein Ubiquitination" Biochemistry 2008, 47, 3636-3644.
  9. Yizhong Wang, Claudia Rivera Vera, and Qing Lin* "Convenient Synthesis of Highly Functionalized Pyrazolines via Mild, Photoactivated 1,3-Dipolar Cycloaddition" Org. Lett. 2007, 9, 4155-4158.
  10. Jiazhi Sun, Michelle Blaskovich, Rishi K. Jain, Frederic L. Delarue, Daniel Paris, Steven Brem, Marguerite Wotocezk-Obadia, Qing Lin, Domenico Coppola, Kihang Choi, Michael Mullan, Andrew D. Hamilton and Saïd M. Sebti "Blocking Angiogenesis and Tumorigenesis with GFA-116, a Synthetic Molecule that Inhibits Binding of Vascular Endothelial Growth Factor to its Receptor" Cancer Research 2004, 64, 3586-3592.
  11. Qing Lin, Carlos F. Barbas III and Peter G. Schultz "Small Molecule Switches for Zinc Finger Transcription Factors"J. Am. Chem. Soc. 2003, 125, 612-613.
  12. Qing Lin and Andrew D. Hamilton "Design and Synthesis of Multiple-Loop Receptors Based on a Calix[4]arene Scaffold for Protein Surface Recognition" C. R. Chimie 2002, 5, 441-450.
  13. Hyung Soon Park, Qing Lin and Andrew D. Hamilton "Modulation of Protein-Protein Interactions by Synthetic Receptors: Design of Molecules That Disrupt Serine Protease-Proteinaceous Inhibitor Interaction" Proc. Natl. Acad. Sci. USA 2002, 99, 5105-5109.
  14. Qing Lin, Fanyi Jiang, Peter G. Schultz and Nathanael Gray "Design of Allele-Specific Protein Methyltransferase Inhibitors" J. Am. Chem. Soc. 2001, 123, 11608-11613.
  15. Yen Wei, George L. McLendon, Andrew D. Hamilton, Martin A. Case, Cherie B. Purring, Qing Lin, Hyung Soon Park, Chang-Sun Lee and Tianning Yu "Disruption of Protein-Protein Interactions: Design of A Synthetic Receptor that Blocks the Binding of Cytochrome c to Cytochrome c Peroxidase", Chem. Commun. 2001, 1580-1581.
  16. Michelle Blaskovich, Qing Lin, Frederic L. Delarue, Jiazhi Sun, Domenico Coppola, Hyung Soon Park, Andrew D. Hamilton and Saïd M. Sebti "Design of GFB-111 a Platelet-Derived Growth Factor Binding Molecule with Anti-Angiogenic and Anti-Cancer Activity Against Human Tumors in Mice" Nature Biotechnol. 2000, 18, 1065-1070.
  17. Hyung Soon Park, Qing Lin and Andrew D. Hamilton "Protein Surface Recognition by Synthetic Receptors: A Route to Novel Sub-micromolar Inhibitors for α-Chymotrypsin" J. Am. Chem. Soc. 1999, 121, 8-13.
  18. Qing Lin, Hyung Soon Park, Yoshitomo Hamuro, and Andrew D. Hamilton "Protein Surface Recognition by Synthetic Receptors" in Supramolecular Science: Where It Is and Where It Is Going, Ungaro, R., Dalcanale, E. Ed. Kluwer, Amsterdam, 1999, 197-204.
  19. Andrew D. Hamilton, Hyung Soon Park, Qing Lin and Rishi Jain "Towards Artificial Antibodies: Protein Surface Recognition by Synthetic Receptors" in Peptides for the New Millennium, Fields, G.B.; Tam, J.P.; Barany, G. Eds., Kluwer, Dordrecht, 1999, 531-533.
  20. Qing Lin, Hyung Soon Park, Yoshitomo Hamuro, Chang-Sun Lee and Andrew D. Hamilton "Protein Surface Recognition by Synthetic Agents: Design and Structural Requirements of a Family of Artificial Receptors that Bind to Cytochrome c" Biopolymers, 1998, 47, 285-297.
  21. Qing Lin, Steven J. Geib and Andrew D. Hamilton, "1-Phenyl-1H-Pyrrole-2,5-Dicarboxylic Acid Derivatives as Versatile Hydrogen Bonding Motifs for the Formation of One-, Two- and Three Dimensional Networks in the Solid State" J. Chem. Soc. Perkin Trans. 2, 1998, 2109-2118.

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