Past Organic and Chemical Biology Seminars
Held in the FALL and SPRING semesters
Shortcut to Spring 2012; Fall 2011; Spring 2011; Fall 2010; Spring 2010; Fall 2009; Spring 2009; Fall 2008; Spring 2008; Fall 2007
FALL SEMESTER 2012
Download PDF of the 2012 Fall semester schedule
September 18, 2012
Professor Jonathan F. Lovell
Biomedical Engineering Dept., University at Buffalo
New Biocompatible Supramolecular Structures Formed from Porphyrins and Metalloporphyrins
CANCELED
October 2, 2012
Professor John Richard
Dept. of Chemistry, University at Buffalo
Enzyme Activation by Ligand-Gated Conformational Changes
October 23, 2012
Professor Yingfu Li
Dept. of Chemistry and Chemical Biology, McMaster University
Friend or Foe? Unlocking the Mystery of Bacterial Toxin-Antitoxin Systems
October 30, 2012
Dr. AnnMarie C. O'Donoghue
Dept. of Chemistry, Durham University
Triazolium Catalysis of the Benzoin and Stetter Reactions: New Mechanistic Insights
November 6, 2012
Professor Todd Holyoak
Dept. of Biology, University of Waterloo
The Coupling of Conformational Equilibria and Enzyme Function in Phosphoenolpyruvate Carboxykinase
November 13, 2012
Dr. Peter Fuller
Merck Research Laboratories, Boston, MA
An Aldol-Based Approach Toward Aflastatin A
November 27, 2012
Mr. Avinash Muppidi
Dept. of Chemistry, University at Buffalo
Ph.D. Research Presentation: Conformationally Rigidified Peptide Helices Through the Cysteine-Based Side Chain Cross-Linking
December 4, 2012
Ms. Sarina Dorazio
Dept. of Chemistry, University at Buffalo
Ph.D. Research Presentation: Paramagnetic Iron(II) Complexes as MRI ParaCEST Contrast Agents
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SPRING SEMESTER 2012
Download PDF of the 2012 Spring semester schedule
January 31, 2012
Professor Anthony Auerbach
Dept. of Physiology & Biophysics, University at Buffalo
“Design and Control of Acetylcholine Receptors”-- It’s Mainly Single-Molecule Kinetics
February 21, 2012
Ms. Bogdana Goryanova
Dept. of Chemistry, University at Buffalo
Ph.D. Research Presentation: Orotidine Monophosphate Decarboxylase: Study of the Mechanism of Stabilization of the Reaction Intermediate
February 28, 2012
Professor Daniel J. Weix
Dept. of Chemistry, University at Rochester
No More Nucleophiles: Direct Cross Coupling of Electrophiles
March 13, 2012
Professor Tetsuya Satoh
Dept. of Applied Chemistry, Osaka University
Chelation-Assisted Oxidative C-H Functionalization under Transition-Metal Catalysis
March 20, 2012
Mr. Michael Bovino
Dept. of Chemistry, University at Buffalo
Ph.D. Research Presentation: The Copper(II) Catalyzed Enantioselective Aminohalogenation of Unactivated Alkenes
March 27, 2012
Professor Robert Bartha
Dept. of Medical Biophysics, Robarts Research Institute, University of Western Ontario
Paramagnetic Chemical Exchange: Shifting Sights for In-vivo MRI
April 3, 2012
Mr. Justin Bolton
Dept. of Chemistry, University at Buffalo
Ph.D. Research Presentation: Synthesis and Self-Assembly of Asymmetric Bottlebrush Copolymers
April 10, 2012
Professor Kenneth E. Maly
Dept. of Chemistry, Wilfrid Laurier University
Synthesis and Self-Assembly of Novel Polycyclic Aromatic Hydrocarbons
April 17, 2012
Mr. Benjamin Turnpenny
Dept. of Chemistry, University at Buffalo
Ph.D. Research Presentation: Intra/Intermolecular Copper(II) Catalyzed Diamination of Alkenes
April 24, 2012
Mr. Edgars Jecs
Dept. of Chemistry, University at Buffalo
Ph.D. Research Presentation: Total Synthesis of Amphidinolide P
May 1 , 2012
Ms. Alexandra Orchard
Dept. of Chemistry, University at Buffalo
Ph.D. Research Presentation: Novel Chalcogenorhodamine Compounds with Myriad Applications
FALL SEMESTER 2011
Download PDF of the 2011 Fall Semester schedule
September 13, 2011
Professor Daniel J. Kosman
Dept. of Biochemistry, University at Buffalo
Iron Trafficking in Water Under Air: Dealing with Iron's Pourbaix Diagram
September 20, 2011
Ms. Reyna Koreen Lim
Dept. of Chemistry, University at Buffalo
Ph.D. Research Presentation: "Towards the Development of Sequence-specific Bioorthogonal Reactions"
October 4, 2011
Dept. of Biological Sciences, University at Buffalo
Look, but Don’t Touch-Mechanism of Indirect Readout of DNA Sequence by Proteins
October 11, 2011
Dr. Richard L. Pederson
Materia, Inc.
Commercial Applications of Olefin Metathesis
October 18, 2011
Dept. of Chemistry, University of Pittsburgh
Protein Complex Assemblies and Activities at the DNA Replication Fork
CANCELED
October 25, 2011
Dept. of Biochemistry & Medical Sciences, McMaster University
100 fs of Enzymology: Transition State Analysis of Enzymatic Reactions
November 1, 2011
Dept. of Chemistry & Chemical Biology, Cornell University
The Enzymatic Activity of Sirtuins: Beyond NAD-dependent Deacetylation
November 8, 2011
Dept. of Chemistry, Brock University
Identifying Biologically Significant Coupled Motions in Biomolecular Simulation Data
November 15, 2011
Dr. Andrew Bell
Promerus LLC
Addition Polymerized, Functional Norbornene-Type Monomers via High Activity Palladium Catalysts for Electronic Materials
Download PDF of the 2011 Spring Semester schedule
January 25, 2011
Professor Michael J. Buck
Dept. of Biochemistry, NYS Center of Excellence in Bioinformatics and Life Sciences, Buffalo, NY
ChIPing into Chromatin: Determining How Chromatin Structure Regulates Transcription Factor Targeting
February 15, 2011
Ms. Monissa Paderes
Dept. of Chemistry, University at Buffalo
Ph.D. Research Presentation: "Stereoselective Synthesis of Nitrogen Heterocycles via Copper(II)-Catalyzed and Promoted Intramolecular Alkene Aminooxygenation"
February 22, 2011
Ms. M. Merced Malabanan
Dept. of Chemistry, University at Buffalo
Ph.D. Research Presentation: "Phosphite Activation of the Proton Transfer Reaction Catalyzed by Triosephosphate Isomerase"
March 1, 2011
Ms. Fatima Sequeira
Dept. of Chemistry, University at Buffalo
Ph.D. Research Presentation: "Increasing the Utility of Stereoselective Copper-Promoted and Catalyzed Alkene Diamination and Aminooxygenation"
March 8, 2011
Dept. of Macromolecular Science and Engineering, Case Western Reserve University
Supramolecular Approaches to Stimuli-Responsive Materials: From Sea Cucumbers to Self-Healing Films
March 22, 2011 (in NSC 684)
Dr. Grant E. DuBois
The Coca-Cola Company
The Chemical Senses: Mechanism of Action and Mechanism-Guided Transformational Innovation
March 29, 2011 (in NSC 684)
Professor Roopa ThaparDept. of Structural Biology, Hauptman-Woodward Institute
Structural Insights into Histone Pre-mRNA Processing and Its Regulation by Phosphorylation
WED., April 6, 2011
Professor Zachary T. BallDept. of Chemistry, Rice University
Diverse Structures and Functions of Dirhodium Metallopeptides
April 12, 2011 (in NSC 684)
Professor Nancy I. TotahDept. of Chemistry, Syracuse University
Synthesis of Tetrahydropyran Containing Natural Products
April 19, 2011 (in NSC 684)
Professor Stacey E. BrennerDept. of Chemistry, Brooklyn College
Novel Organocascade Reactions
April 26, 2011 (in NSC 684)
Professor Kara L. BrenDept. of Chemistry, University of Rochester
Functional Consequences of Covalent Attachment of Heme c to Proteins
CANCELED
May 3, 2011 (in NSC 684)
Ms. Reyna Lim
Dept. of Chemistry, University at Buffalo
Ph.D. Research Presentation
Fall Semester 2010
Download PDF of the 2010 Fall Semester schedule
September 14, 2010
Professor Timothy C. Umland
Hauptman-Woodward Medical Research Institute
Identification of New Antibiotic Targets in Gram Negative Bacteria
September 28, 2010
Case Western Reserve University, Center for RNA Molecular Biology
Quantitative Analysis of RNA-Metal Ion Interactions by Raman Spectroscopy
October 5 , 2010
Case Western Reserve University, Department of Chemistry
Small Molecule Modulation of Expression in the Inflammatory Response
October 19 , 2010
University of Rochester, Department of Chemistry
Peptide Self-Assembly: From Amyloid to Engineered Biomaterials
November 2 , 2010
University at Buffalo, Department of Chemistry
A Role for Flexible Loops in Enzyme Catalysis
November 16 , 2010
Dr. Lawrence Goldman
University at Buffalo, Department of Chemistry
Critical Tests for Nonstatistical Dynamics in Organic Systems
November 30 , 2010
Professor Harry A. SternUniversity of Rochester, Department of Chemistry
Computational Estimation of Protein-Ligand Binding Affinities
Spring Semester 2010
Download PDF of the 2010 Spring Semester schedule
February 2, 2010
Professor Debashis Ghosh
Hauptman-Woodward Research Institute
The Unique Biochemistry of Androgen Aromatization by Cytochrome P450 Aromatase: A Structural Perspective
February 9, 2010
Department of Chemistry, University at Buffalo
Structure-Reactivity Effects on Proton Transfer Reactions: Brønsted Coefficients and Kinetic Isotope Effects
February 23, 2010
Department of Chemistry, Texas A&M University
Fluorescent Probes for Multiplexed Intracellular Imaging
March 2, 2010
Dr. R. Jason Herr
Medicinal Chemistry Department, Albany Molecular Research, Inc.
Tales from the Chemistry Skunk Works: Academic Projects Run in an Industrial Setting
March 30, 2010
Mr. Brandon Calitree
Department of Chemistry, University at Buffalo
Generating Renewable Energy Using Rhodamine Analogues
April 6, 2010
Dr. Deepak Shukla
Kodak Research Labs, Eastman Kodak Company
Effect of Configurational Control on Charge Mobility in Naphthalene Diimide-Based Organic Field Effect Transistors
CANCELLED
April 13, 2010
Department of Chemistry, Syracuse University
Carbon-Carbon Bond Forming Reactions of 2-Methylenetetrahydropyrans
April 20, 2010
Professor Kathleen L. BerknerMolecular Cardiology Department, Lerner Research Institute, Cleveland Clinic
New Insights into the Mechanism of Vitamin K-dependent Protein Carboxylation, a Complex Process with Broad Physiological Impact
Fall Semester 2009
A PDF version of the semester schedule is available here.
September 10, 2009
Professor David M. Birney
Dept. of Chemistry and Biochemistry, Texas Tech University
Pseudopericyclic Reactions – Adventures on Potential Energy Surfaces
September 15, 2009
Dept. of Chemistry and Biophysics, University of Rochester
Case Studies of Functional RNA Molecules: From Metabolite Recognition to Catalysis
September 22, 2009
Ms. Shonoi A. Barnett
Dept. of Chemistry, University at Buffalo
Studies on the Mechanism of Action of OMP Decarboxylase
September 30, 2009
Dept. of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey
Enantioselective Organocatalysis and the Study of Redox Neutral Reaction Cascades
October 6, 2009
Dept. of Chemistry, University of Rochester
Modeling Secondary and Local 3D Structure of an R2 Retrotransposon
October 13, 2009
Terrence Donnelly Centre for Cellular & Biomolecular Research, University of Toronto
Deciphering and Modulating Cellular Signaling with Combinatorial Biology
October 20, 2009
Dr. Kazuhiro Yamato
Dept. of Chemistry, University at Buffalo
Aggregation and Binding Study of Shape-Persistent Oligomers
October 27, 2009
Dept. of Chemistry, University at Buffalo
Enzymatic Transition States from Kinetic Isotope Effects: Blueprints for Inhibitor Design
November 3, 2009
Dr. Pavel Tsitovich
Dept. of Chemistry, University at Buffalo
Microarrays to Study Antibiotic Resistance
November 10, 2009
Dept. of Biochemistry and Biomedical Sciences, McMaster University
Chemical Genomics: Charting Chemical-Genetic Interactions in Bacteria
November 17, 2009
Ms. Wenjiao Song
Dept. of Chemistry, University at Buffalo
A Tetrazole-Based Bioorthogonal Reaction for Protein Imaging in Live Cells
Spring Semester 2009
There were no Organic or Chemical Biology Seminars during the Spring 2009 semester.
Fall Semester 2008
There were no Organic or Chemical Biology Seminars during the Fall 2008 semester.
Spring Semester 2008
A PDF version of the semester schedule is available here
January 30, 2008
Professor John Richard
Department of Chemistry University at Buffalo
Flexible Protein Loops and Enzymatic Catalysis of Proton Transfer, Hydride Transfer and
Decarboxylation Reactions
February 13, 2008
Professor Daniel Gewirth
Structural Biology
Hauptman-Woodward Medical Research Institute
Structure and Function of Hsp90 Chaperones
February 20, 2008
Professor Yoshihisa Kobayashi
Department of Chemistry and Biochemistry University of California, San Diego
Heterocycles in Natural Product Synthesis
February 27, 2008
Professor Kiong Ho
Department of Biological Sciences University at Buffalo
Mechanism of Action of RNA Ligase
March 5, 2008
Dr. Craig Williams
School of Molecular and Microbial Sciences
University of Queensland, Australia
"So Close But Yet So Far Away". Towards the Total Synthesis of Various Vibsane Diterpenes
March 19, 2008 (Cancelled)
Professor Debashis Ghosh
Hauptman-Woodward Medical Research Institute
Aromatase and Estrogen Biosynthesis: A View from the Real Structure!
March 26, 2008
Dr. Akin Davulcu
Bristol-Myers Squibb
From the Bench to the Plant: Case Studies in the Development and Scale Up of Chemical Processes
April 2, 2008
Professor Michael Yu
Department of Biological Sciences University at Buffalo
Regulation of Gene Expression by Protein Arginine Methylation
April 23, 2008
Professor Bing Gong
Department of Chemistry University at Buffalo
Directed Molecular Association, Folding, and Macrocyclization: Bioinspired Systems
Fall Semester 2007
A PDF version of the semester schedule is available here
September 5, 2007
Professor Ohyun Kwon
Department of Chemistry & Biochemistry University of California, Los Angeles
Phosphine Catalysis of Allenes in Target-Oriented Synthesis (TOS) and Diversity-Oriented Synthesis (DOS)
September 12, 2007
Professor Andrew Phillips
Department of Chemistry & Biochemistry University of Colorado at Boulder
From Targets to Strategies and Back Again: Some Examples from Complex Molecule Synthesis
September 19, 2007
Professor Stephen L. Buchwald
Department of Chemistry Massachusetts Institute of Technology
Transition Metal-Catalyzed Carbon-Carbon and Carbon-Heteroatom Bond-Forming Processes: Progress, Applications and Mechanistic Studies
November 7, 2007
Professor Glenn Micalizio
Department of Chemistry Yale University
Group IV Metal-Mediated Reactions for Carbon-Carbon Bond Formation: Cross-Coupling via Directed Carbometalation



